RESP® for Chronic Cough
Elevate your understanding of treatment effects on cough burden
Chronic cough, which impacts between 10-20% of the US population,1 can be both a symptom of another health condition, such as idiopathic pulmonary fibrosis (IPF) or asthma, or a disease without an underlying cause. More than an annoyance, chronic cough can significantly impact quality of life, including interrupting sleep and disrupting social life.2,3
Despite cough’s prevalence and impact, there remains a lack of reliable, patient-friendly technologies for objectively measuring cough in daily life. The RESP® Biosensor provides an optimal solution for assessing cough burden in clinical trials alongside patient-reported outcomes, delivering accurate and granular insights while accelerating timelines.
Technology Overview
The RESP® Biosensor is a leading, high-fidelity cough monitoring technology designed for measuring treatment effects on cough in patients’ daily lives. Our technology offers:
- A wireless, discreet design that respects patient comfort and lifestyle
- Direct cloud syncs that expedite analysis of cough measures and streamline patient reports
- Novel measures, such as cough intensity, that lead to a greater understanding of overall cough burden
How It Works
A fit-for-purpose solution for cough monitoring in clinical trials
RESP® Biosensor
Wearable biosensor passively and continuously collects lung sounds
RESP® Cloud
Captured data are securely and wirelessly transferred to HIPAA-compliant cloud for cough annotation
Cough Reports
Client receives subject cough reports
Why the RESP® Biosensor for Cough Monitoring?
Privacy & Security
Incorporates end-to-end encryption and speech obfuscation to preserve patient privacy
Seamless & Streamlined
Cloud-based syncs from paired mobile phones allow for remote data uploads, accelerating subject reporting
High Fidelity & Integrity
FDA 510(k) class II medical device for capturing lung sounds, including cough
Patient-Friendly Form Factor
Wireless, discreet biosensor secured by a gentle and breathable adhesive
Granular Insights
Gain a greater understanding of cough burden beyond cough counts, including cough intensity, breathing patterns, vitals, and other physiological data.
Cough Monitoring Applications with RESP®
Rapid, Reliable Subject Screening
Primary, Secondary & Exploratory Endpoints or Sub-Studies
Post-Approval, Real-World Evidence Studies
Download the Strados Publication
Quantification of Cough Intensity during Cough Bouts by the RESP® Biosensor System
Flexible Reporting—Automated or Human Annotation
- Strados Labs’ trained and qualified annotation team identifies and counts cough and lung sound events from subject recordings to meet primary endpoint requirements.
- Our CoughCheck™ machine learning algorithm*, trained on over 200,000 coughs, has demonstrated strong accuracy in cough detection and is available for applications such as high-volume screening or exploratory endpoints.
*Algorithm not FDA-cleared but may be used in clinical trials
Publications
OVERVIEW VIDEO
Learn more about the benefits of the RESP Biosensor for Cough Monitoring
Let’s Connect
Explore using the RESP® Biosensor in your study or practice
References
- Chronic Cough: Causes & Treatment. Cleveland Clinic. https://my.clevelandclinic.org/health/symptoms/15048-chronic-cough-overview
- French, C. L., Irwin, R. S., Curley, F. J., & Krikorian, C. J. (1998). Impact of chronic cough on quality of life. Archives of internal medicine, 158(15), 1657–1661. https://doi.org/10.1001/archinte.158.15.1657
- Chamberlain, S. A., Garrod, R., Douiri, A., Masefield, S., Powell, P., Bücher, C., Pandyan, A., Morice, A. H., & Birring, S. S. (2015). The impact of chronic cough: a cross-sectional European survey. Lung, 193(3), 401–408. https://doi.org/10.1007/s00408-015-9701-2