RESEARCH & CLINICAL TRIALS
RESP® Biosensor
Continuous lung sound and cough monitoring for greater insights in research studies and drug development
FDA 510(k) Class II Device | CE Mark | HIPAA Compliant
Cough and wheeze are highly prevalent, burdensome symptoms across many respiratory and infectious diseases. Patient-reported outcomes (PROs), while valuable, may not fully capture the reality these symptoms present. The RESP® Biosensor measures the full scope of respiratory symptoms, providing greater insight in clinical trials and research alongside PROs and pulmonary function tests.
Technology Overview
The RESP® Biosensor allows researchers and drug developers to objectively measure patients’ cough and lung sounds in Phase I – IV clinical trials. Optimized for ease of use at home, our cough monitoring device offers:
- Patient-Friendly Form Factor: A wireless, discreet design that respects patient comfort and lifestyle.
- Rapid, Reliable Data Access: Direct cloud sync facilitates efficient analysis of objective respiratory metrics.
- Comprehensive Data: Respiratory measurements provide greater insights into treatment response and differentiation for clinical programs and candidates.
RESP® Biosensor Measures
Cough Monitoring
24-Hour Cough Frequency, Intensity* and Bouts
Lung Sounds
Additional Insights*
*For investigational use only
Trusted By
Why Choose the RESP® Biosensor for Cough Monitoring?
Privacy & Security
Incorporates end-to-end encryption and advanced noise filtering for preserve patient privacy.
Accelerated Data Turnaround
Real-time, cloud-based syncs from paired mobile device streamline data reporting and overread process.
Subject Cough Only
Multi-modal data are used to differentiate between subject coughs and external coughs.
Patient-Friendly Form Factor
Low-burden, sleek design aids patient comfort and compliance while mirroring real-life conditions.
Comprehensive Insights
Extended measurements beyond cough frequency allow for a greater understanding of lung health and subject quality of life.
Metrics-at-a-Glance
700k+
Validated Coughs Captured
20m+
Breaths Captured
4
35
2
1
Clinical Evidence
The value and clinical validation of the RESP Biosensor has been presented at several respiratory conferences including the American Thoracic Society and CHEST.
RESP® Biosensor Therapeutic Areas
Using a combination of audio and motion data, the RESP Biosensor unlocks valuable insight across multiple indications, offering a more complete picture of subjects’ respiratory status and health-related quality of life alongside PROs.
| Cough | Wheeze | Crackles | Respiratory Rate* | Activity Levels* | Sleep/Wake* | Body Positioning* | |
| Chronic Cough | |||||||
| IPF | |||||||
| Bronchitis | |||||||
| COPD | |||||||
| Asthma | |||||||
| RSV | |||||||
| Covid-19 | |||||||
| Heart Failure |
- Chronic Cough
- IPF
- Bronchitis
- COPD
- Asthma
- RSV
- Covid-19
- Heart Failure
*For investigational use only
The Cough Monitoring Device Patients Prefer
- Compared to bulkier alternatives, the RESP Biosensor reduces patient burden.
- Wireless and discreet, patients report that they forget the cough monitoring device is on and that it doesn’t interfere with daily routines.
- Sleek design helps ensure patients behave naturally, capturing authentic symptom data that mirrors real-life conditions and minimizes the Hawthorne effect.
Validated Overread and Event Annotation Process
- Our cough counting approach includes a consensus labeling process to ensure the highest level of accuracy and to meet endpoint requirements.
- Machine learning algorithms* for automated cough counting have also been performance-tested to meet customer requirements.
- Algorithms* allow for compression of cough recordings for human annotation or can be used independently for subject screening and other applications.
**Machine learning algorithms not FDA-cleared
Visual spectrograms of lung sound events facilitate overread for trained specialists
Cough
Wheeze
Crackles
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Explore using the RESP® Biosensor in your next study