Poster Presentation
European Respiratory Society Congress 2025
Objectively Quantifying the Burden of Cough Bouts in Chronic and Subacute Cough
Tom deLaubenfels, Richard Powers, Jason Kroh, Adrian Marinovich, MD, Allison Sees
What’s Inside?
This abstract evaluates cough amplitude as a new objective measure of cough severity using the RESP® Biosensor, extending beyond traditional cough frequency metrics. Continuous, real-world recordings were collected from 360 participants presenting with chronic or subacute cough. Cough events and bouts, defined as clusters of two or more coughs separated by less than two seconds, were identified by trained annotators, and cough intensity was calculated using peak RMS amplitude.
Across both groups, the average number of coughs per bout was similar (≈3 coughs per bout), but the proportion of coughs occurring in bouts differed slightly—66% in chronic cough and 74% in subacute cough. Notably, mean cough intensity during bouts was 39% higher in chronic cough compared to isolated coughs, while subacute cough bouts were slightly less intense (-3%).
These findings highlight the potential of novel measures such as cough intensity to assess cough burden.