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Strados FeNO

Fractional Exhaled Nitric Oxide

NObreath® — Point-of-Care FeNO Measurement

A rapid, reliable biomarker for Type 2 airway inflammation. FeNO measurement provides objective evidence of eosinophilic inflammation to support patient stratification, endpoint assessment, and treatment monitoring in respiratory trials.

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Capabilities

Key Features

Rapid Results

Results available within seconds at the point of care. No lab processing or sample shipping required.

Patient Stratification

Identify and enrich for Type 2 high patients at screening to improve trial population selection.

Treatment Monitoring

Track inflammatory response over time to demonstrate pharmacodynamic effect of anti-inflammatory therapies.

Validated Biomarker

Established correlation with eosinophilic airway inflammation. Recognized by ATS/ERS clinical guidelines.

Simple Technique

Non-invasive breath test with guided flow rate control for reproducible measurements across sites.

Portable Device

Compact, portable design for easy deployment across global trial sites with minimal site training.

Clinical Value

FeNO as a clinical trial endpoint

FeNO provides a non-invasive, reproducible measure of airway inflammation that complements pulmonary function and patient-reported outcomes.

1

Enrich study populations

Use FeNO at screening to select patients with Type 2 inflammation, improving response rates and signal detection.

2

Pharmacodynamic endpoint

FeNO change from baseline provides objective evidence of anti-inflammatory mechanism of action.

3

Complement spirometry

FeNO captures inflammatory status that spirometry alone cannot assess, adding dimension to your endpoint strategy.

4

Reduce sample size requirements

Better patient selection through FeNO-based enrichment can reduce the number of subjects needed for adequate power.

Strados Intelligence Advantage

Reliable supply for your clinical trial

NObreath® offers consistent global availability, portable design, and minimal site training — solving the supply constraints that often limit Niox deployment in clinical trials. Strados partnerships ensure dedicated supply chains and white-glove logistics support for uninterrupted enrollment.

Part of the Strados Endpoint Suite

FeNO + the full endpoint suite

Combine FeNO with spirometry, cough monitoring, and eCOA to build the most complete picture of respiratory disease status and treatment response.

Ready to design your respiratory study?

Tell us about your program and we'll help you design the right respiratory endpoint strategy.

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