The Evolution of Objective Cough Monitoring: Building on a Strong Foundation
Chronic cough has proven to be one of the more challenging therapeutic areas in respiratory medicine. Despite years of scientific progress, significant investment, and multiple late-stage clinical development programs, there are still no FDA-approved therapies available for refractory or unexplained chronic cough in the United States, a condition that affects more than 12 million people.1 […]
How Can Monitoring Cough & Lung Sounds Add Value in Respiratory Clinical Trials?
While regulators may not require objective cough and/or lung sound monitoring outside of chronic cough studies, sponsors increasingly recognize that relying solely on pulmonary function tests and patient-reported outcomes leaves critical insight on the table. In conditions such as pulmonary fibrosis, bronchiectasis, COPD, and asthma where cough and lung sounds such as wheezing are highly […]
Q/A with Dr. Sabiha Hussain, Professor of Medicine at Robert Wood Johnson Medical School, Rutgers Health
Dr. Sabiha Hussain is the principal investigator of RWJ Barnabas Health’s research study evaluating the RESP® Biosensor for wearable respiratory monitoring in cystic fibrosis. The Strados team was fortunate to meet for a short interview with Dr. Hussain. What motivated you to initiate this study, and what key questions are you hoping to answer using […]
From Stethoscope to Sensor: How We Developed a Lung Acoustics Wearable
The advent of wearable technology is changing how we monitor health across a range of conditions, offering continuous, real-world insights into patients’ vitals and physiological data. At Strados Labs, our goal was to develop a wearable specifically for monitoring patients with chronic respiratory diseases such as COPD and asthma. Our approach? Model our technology after […]
Cough Counting Approaches Explained: Which One Is Best?
Cough monitoring, namely for the measurement of cough frequency, has seen increased interest and use in clinical trials to provide a greater understanding of treatment effects on subjects’ cough. As sponsors and researchers evaluate cough monitoring technologies for their studies, an important aspect to consider is the cough counting method used to determine cough frequency. […]
Takeaways from the ATS 2025 Innovation Hub Session: Tuning In To Cough In Pulmonary Fibrosis
At this year’s ATS conference, Strados Labs was proud to host the session, “Tuning In To Cough in Pulmonary Fibrosis: How Should We Address the Gap?” presented by Dr. Toby Maher, Professor of Clinical Medicine at the Keck School of Medicine, USC. The talk focused on cough in pulmonary fibrosis, a highly prevalent, debilitating symptom […]
Tuning In To Cough in Pulmonary Fibrosis: How Should We Address the Gap?
ATS 2025 Innovation Hub PresentationToby Maher, MD, PHD, Professor of Clinical Medicine at Keck School of Medicine, USC
Regulatory Pathways for Cough Monitoring in Clinical Trials: FDA Validation Requirements Explained
Cough monitoring has emerged as an increasingly common practice in research studies and drug development in recent years to objectively measure changes in subjects’ cough. As drug developers consider including cough frequency as an endpoint in their studies, understanding the current regulatory pathway and the FDA’s validation requirements is essential. To support trial sponsors, we’ve […]
Why the Tegaderm™ Adhesive is a Trusted, Patient-Friendly Solution for the RESP® Biosensor
In research studies and healthcare settings, minimizing patient burden is essential for reliable data collection with wearables and devices. At Strados Labs, we understand the importance of these factors with the RESP® Biosensor, which is designed to continuously capture lung sounds such as coughing and wheezing in daily life. A critical part of the RESP […]
Cough as an Endpoint in IPF Trials: Why it Matters
Increased importance has been placed in recent years on the ability of idiopathic pulmonary fibrosis (IPF) treatments to impact how patients feel and function, beyond survival (Raghu, et al., 2024). In IPF, one of the most burdensome symptoms impacting how patients feel and function is a dry, persistent cough. Due to its consistent correlation with […]